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3 simple ideas for overcoming childhood obesity

Kristopher Kaliebe, MD, Clinical Assistant Professor of Psychiatry at the LSU Health Sciences Center New Orleans School of Medicine, offers parents and caregivers three simple family-oriented goals to overcome the complex problem of childhood obesity and related mental disorders.

Dr. Kaliebe's "rules," meant to facilitate healthy choices, are straightforward and practical.

1. Eat Food – Not too Much, Mostly Plants. Dr. Kaliebe explains that eating natural, unprocessed, raw food eliminates the constant need to calculate calories, carbohydrates, fat, protein, vitamins, etc. – a reason diets fail. This rule also advises severely restricting foods like chips, sodas and fast food.

2. Get Up and Move. Noting that humans are not built to sit for much of the day, Dr. Kaliebe says children as well as parents need to find excuses to move whenever possible and be especially active during leisure time.

3. Honor Silence. Dr. Kaliebe says sensory overload and "noise" from popular culture, gaming, advertising, media and electronics crowds out important things such as family matters, academics, sleep, and the development of other interests. "Habits have profound effects," concludes Dr. Kaliebe. "Celebrations, such as birthday parties, are less meaningful. Don't stress over the occasional special treat, but be strict about everyday routines."
Louisiana State University Health Sciences Center. Journal of the American Academy of Child and Adolescent Psychiatry. 042014



A new weapon in the fight against obesity and diabetes

New SIRT1 activator protects against metabolic diseases associated with a high fat diet

A study appearing 5 Nov 2008 in the journal Cell Metabolism demonstrates that a synthetic new chemical entity protects against diet-induced obesity, improves glucose tolerance and insulin sensitivity and enhances exercise endurance by enhancing fat utilization in certain target tissues. 

The new chemical entity was developed by Sirtris, a a GSK company, and the research study was led by EPFL professor Johan Auwerx, MD.

Reducing calorie consumption by about 20% has been shown to slow down the aging process, improve endurance and protect against diet-induced obesity and metabolic diseases such as diabetes. A year ago, researchers demonstrated that these metabolic benefits can also occur with large doses of resveratrol, a substance naturally occurring in red wine. Researchers hypothesized that these beneficial effects result from activation of SIRT1, an enzyme that is involved in regulating certain key cellular processes, notably the efficiency and number of mitochondria – the energy powerhouses of our cells. 

Because dietary management and exercise rarely succeed by themselves in curbing obesity and associated metabolic disorders, interest has increased in using the SIRT1 pathway as a target for possible pharmacological intervention.

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